The Progress of Pancreatic Cancer Research


(gentle instrumental music) – So people ask why is pancreatic cancer such a difficult problem? Why has it been so hard to cure? First, it’s not a cancer
caused by a single problem. One of the primary reasons
that pancreas cancer has been so difficult, is because of a particular driver of the cancer called KRAS. This KRAS mutation, so far, has resisted all of our attempts to
shut it down using a drug. – So one of the reasons pancreas cancer is so deadly is it’s often found late, when it’s spread elsewhere
throughout the body. For unknown reasons, at a very small size, it tends to spread through the bloodstream to places like the liver, lungs, and bone, and we are currently working on strategies to determine why this
happens and ways to fix it. – Doctors have tried to
treat pancreatic cancer like any other tumor and use chemotherapy, but most pancreatic cancers are highly resistant to chemotherapy. So, the best chance of treatment is to develop drugs that
are specific for the tumor and to do that we need to
understand the biology, we need to understand the
cell types in the tumor and what signals keep them alive, so that we can block those signals to eliminate the tumor cells. – So collaboration is critical for doing pancreatic cancer research. I mean, we’ve had very few
pancreatic cancer researchers historically come into the field, and now we’ve been
encouraging people to move into the field, work with us, add their ideas to the mix
of what we already knew, and I have to say that no one individual knows enough to conquer this cancer, it’s just a horrifying disease and if we were smart
enough on our own to do it, we’ve already would have fixed it. We already would have cured it. – There are a number
of things that make me optimistic about the immediate and distant future for pancreas cancer research. I think that a lot of
research that’s been done at the University of
Michigan and elsewhere are coming to identify
potential strategies with which the barrier
that pancreas cancer poses against the immune system can
be broken down a little bit, and if that happens, then these almost miraculous therapies that are becoming available for people with other types of cancers, I really believe will also make their way into the lives of people
with pancreas cancer as well. – The hope, the vision, is to increase the immune infiltration
into the pancreas cancer. So it’s very promising because it probably will allow us to create a memory of what needs to be attacked, and if we’re able to do so, then we can not only have a
fantastic response to therapy but also keep that cancer at bay, because our immune system’s already there, it has the memory, it will identify the cells as
soon as they emerge or recur, and kill them. – In the long term, it is my expectation that immune-based therapies will be the standard of care
for pancreatic cancer, and it is my hope that the
work that we are doing now, understanding the basic mechanisms of immune-based therapies, will lead to the cure
for pancreatic cancer. – So here at the Rogel Cancer Center at the University of Michigan, we’ve created a team of
pancreatic cancer researchers, the Pancreatic Cancer Research Initiative, who are all dedicated to working together and collaborating to
conquering this cancer. We are hopeful that this is the team that will make the progress towards the cure for pancreatic cancer.

4 thoughts on “The Progress of Pancreatic Cancer Research

  1. I was diagnosed with stage 4 lung cancer in 2011, and that year we were excited to be celebrating my six year survivor-ship anniversary – a survival that was not remotely contemplated in 2016. Since i diagnosis i have learnt a lot about lung cancer, the first few years were confronting.

    I had no clue that my LUNG (left) was responsible for these combined symptoms! Fatigue, chest, neck and shoulder pain. My life changed in just one breath when my Doctor diagnosed me with advanced lung cancer that was INOPERABLE, INCURABLE and TERMINAL. I will always remember the pain and tears from my husband’s face as well as my daughters and my close friends. Like many other people this was not the first time that my life was impacted by CANCER. In 2002 my sister was diagnosed with leukemia. Fortunately for us she was diagnosed at an late stage and she pass away. So when my doctor gave the news about me, We all put in mind positive energy to fight against it, Because I was not going to let that put an end to my smile. now i lives a normal healthy and active lifestyle thanks to the “Dr Adebola Herbal Herbs” which my husband doctors prescribed him. SO many good people have lost there life because of greed, The government will preach against herbal herbs because it only one true cure, But will make profit with pills because the money you treat the more money you spent, Thanks to my husband Doctor who told us this. I will want to advice anyone out here going through sorrow with Cancer to reach out to Dr Adebola and I guarantee you that you will be cured. Contact him via: ([email protected])

  2. I was diagnosed with stage 4 lung cancer in 2011, and that year we were excited to be celebrating my six year survivor-ship anniversary – a survival that was not remotely contemplated in 2016. Since i diagnosis i have learnt a lot about lung cancer, the first few years were confronting. I had no clue that my LUNG (left) was responsible for these combined symptoms! Fatigue, chest, neck and shoulder pain. My life changed in just one breath when my Doctor diagnosed me with advanced lung cancer that was INOPERABLE, INCURABLE and TERMINAL. I will always remember the pain and tears from my husband’s face as well as my daughters and my close friends. Like many other people this was not the first time that my life was impacted by CANCER. In 2002 my sister was diagnosed with leukemia. Fortunately for us she was diagnosed at an late stage and she pass away. So when my doctor gave the news about me, We all put in mind positive energy to fight against it, Because I was not going to let that put an end to my smile. now i lives a normal healthy and active lifestyle thanks to the “Dr Adebola Herbal Herbs” which my husband doctors prescribed him. SO many good people have lost there life because of greed, The government will preach against herbal herbs because it only one true cure, But will make profit with pills because the money you treat the more money you spent, Thanks to my husband Doctor who told us this. I will want to advice anyone out here going through sorrow with Cancer to reach out to Dr Adebola and I guarantee you that you will be cured. Contact him via: ([email protected]) WhatsApp number (+19292018600).

  3. Medical mafia and bureacuracts are holding on cancer research so that only pharmacuticals and hospitals can profit from huge misery cancer creates. Solving problems would crush their money.

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