Pulmonary Hypertension Treatment Explained by Dr. Muhammad Waqas


I’m Dr. Muhammad Waqas. I work at CHI St. Vincent Heart Institute. I specialize in advanced congestive
heart failure and pulmonary hypertension. For treatment strategies there are three
main pathways that we target in pulmonary hypertension and those targets are based
upon first of all how at what stage the patient is presenting. The sicker the patient is,
the more aggressive the treatment strategy is. Patients who are presenting
in advanced disease state, they almost always end up getting on at least two or
maybe three medications to bring their lung pressures down and help improve the
right heart or right ventricle to get better over time. Those strategies have
shown to improve quality of life in most of those those drug trials and some
other medications have shown to improve survival in long-term as well. This is
one condition which has improved a lot in the last ten years. About ten years
ago we had two or three medications that were approved for the treatment of this
of the disease. Now we have almost 14 different medications which can be
offered to patients with pulmonary hypertension based on relative
conditions where the problem is and how severe or advanced the disease is and we
have a lot more in the pipeline in the next few years which will be coming out
for patients who have pulmonary hypertension and they could be offered
medications which will be a lot less burdensome to carry with them
for the treatment of this condition. Because pulmonary hypertension can be a
condition in itself, or it can be caused by a lot of other conditions which can
lead to pulmonary hypertension. Irrespective of what the cause is, if it is diagnosed
late in the stage of pulmonary hypertension the prognosis is poor so
diagnosing this disease early on in the stage is what improves quality of life
and survival the most. If we catch the disease late, patients suffer longer and
sometimes we cannot offer them the treatment strategies
which were available before to improve the quality of life and survival.

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